camphor-10-sulfonic acid in dichloromethane T=25°C; 0.25 h;

1: 95 percent / CSA / CH2Cl2 / 0.25 h / 25 °C 2: 96 percent / K2CO3 / acetone; methanol / 3 h / 25 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11406415', constants.ctx, '0')">osmium(VIII) oxide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '507437', constants.ctx, '0')">4-methylmorpholine N-oxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '635680', constants.ctx, '0')">acetone</a> <br />T=25&deg;C;&nbsp;5&nbsp;h;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098214', constants.ctx, '0')">hydrogenchloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098229', constants.ctx, '0')">methanol</a> <br />24&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 90 percent / DMAP, pyridine / diethyl ether<br />2: 37 percent / HCl / methanol / 24 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 76 percent / p-TsOH<br />2: 90 percent / DMAP, pyridine / diethyl ether<br />3: 37 percent / HCl / methanol / 24 h<br /> <br /> &nbsp;