3-(二甲氨基)-3-乙氧基-2,2-二氟丙酸乙酯合成路线 （共 7 条）
反应条件
1: ethyl chloro-difluoroacetate With chloro-trimethyl-silane; 1,1-dibromo ethane; zinc in N,N-dimethyl-formamide 2: C5H13NO in N,N-dimethyl-formamide T=60°C; 4 h;
参考文献
Bijeire, Laurent; Denier, Colette; Mulliez, Michel; De Lima, Waldir Tavares
Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 4 p. 881 - 891
参考文献
Tsukamoto, Takashi; Kitazume, Tomoya
Journal of the Chemical Society, Chemical Communications, 1992 , # 7 p. 540 - 541
反应条件
zinc in N,N-dimethyl-formamide
参考文献
Journal of Fluorine Chemistry, , vol. 54, # 1-3 p. 293
反应条件
diethyl sulphate; zinc multistep reaction, other DMF activators; Product distributionMechanism;
参考文献
Tsukamoto, Takashi; Kitazume, Tomoya
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 10 p. 1177 - 1182
反应条件
boron trifluoride diethyl etherate; water 1.) CH2Cl2, 0 deg C, 2.) CH2Cl2, 0 deg C; Multistep reaction;
参考文献
Tsukamoto, Takashi; Kitazume, Tomoya
Chemistry Letters, 1992 , # 7 p. 1377 - 1380
反应条件
sulfuric acid in ethanol 0.166667 h; Ambient temperature;
参考文献
Tsukamoto, Takashi; Kitazume, Tomoya
Journal of the Chemical Society, Chemical Communications, 1992 , # 7 p. 540 - 541
反应条件
boron trifluoride diethyl etherate; water 1.) CH2Cl2, 0 deg C, 2.) CH2Cl2, 0 deg C; Multistep reaction;
参考文献
Tsukamoto, Takashi; Kitazume, Tomoya
Chemistry Letters, 1992 , # 7 p. 1377 - 1380
