8-氧代-1,4-二噁螺[4.5]癸烷-7-羧酸乙酯合成路线 （共 13 条）
反应条件
1: 99 percent / KHMDS / tetrahydrofuran / 1 h / -78 - 21 °C
2: 99 percent / diethyl ether / -78 - 21 °C
View Scheme
参考文献
Gesson; Jacquesy; Mondon
Tetrahedron Letters, 1981 , vol. 22, # 14 p. 1337 - 1340
反应条件
1: 99 percent / KHMDS / tetrahydrofuran / 1 h / -78 - 21 °C
2: 99 percent / diethyl ether / -78 - 21 °C
3: 80 percent / 35percent aq. CF3COOH / CHCl3 / 72 h / 21 °C
View Scheme
参考文献
Py, Sandrine; Harwig, Curtis W.; Banerjee, Srabani; Brown, David L.; Fallis, Alex G.
Tetrahedron Letters, 1998 , vol. 39, # 34 p. 6139 - 6142
反应条件
1: 80 percent / 5percent KOH / H2O / 6 h / Ambient temperature
2: 82 percent / p-toluenesulfonic acid
View Scheme
参考文献
Haga, Kazuo; Oohashi, Masayuki; Kaneko, Ryohei
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 6 p. 1586 - 1590
