3,4,5-三氯哒嗪合成路线

参考文献

CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO); MCNEENEY, Stephen, Phillip; PASTOR FERNÁNDEZ, Joaquín; MARTÍNEZ GONZÁLES, Sonia; MARTÍN HERNANDO, José Ignacio; RODRÍGUEZ HERGUETA, Antonio; RICO FERREIRA, María del Rosario; BLANCO APARICIO, Carmen
Patent: WO2013/4984 A1, 2013 ;
Location in patent: Page/Page column 70 ;

186581-53-3重氮甲烷+

6262-42-6四氯环丙烯

14161-11-63,4,5-三氯哒嗪

参考文献

Lukin, K. A.; Zefirov, N. S.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 2.1 p. 242 - 246
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 2 p. 289 - 294

110-91-8吗啉+

14161-11-63,4,5-三氯哒嗪

21131-12-4

参考文献

Peet
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 5 p. 1389 - 1392

14161-11-63,4,5-三氯哒嗪+

124-41-4甲醇钠

参考文献

Nagashima, Hiromu; Oda, Hirohisa; Hida, Jun-Ichi; Kaji, Kenji
Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 1 p. 421 - 424

14161-11-63,4,5-三氯哒嗪

932-22-94,5-二氯-3-羟基哒嗪

参考文献

Kuraishi
Pharmaceutical Bulletin, 1957 , vol. 5, p. 376,377
Pharmaceutical Bulletin, 1958 , vol. 6, p. 641

14161-11-63,4,5-三氯哒嗪+

611-24-5N-甲基-2-氨基苯酚

27225-84-92-氯-10-甲基-3,4-二氮吩嗪

参考文献

Gortinskaya,T.V. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1971 , vol. 7, p. 698 - 702
Khimiya Geterotsiklicheskikh Soedinenii, 1971 , vol. 7, p. 750 - 754

14161-11-63,4,5-三氯哒嗪+

21892-80-83-甲基-2-苯并恶唑酮

27225-84-92-氯-10-甲基-3,4-二氮吩嗪

参考文献

Gortinskaya,T.V. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1971 , vol. 7, p. 698 - 702
Khimiya Geterotsiklicheskikh Soedinenii, 1971 , vol. 7, p. 750 - 754

14161-11-63,4,5-三氯哒嗪

89180-50-7+

53180-76-04-氨基-3,5-二氯哒嗪

参考文献

Journal of Heterocyclic Chemistry, , vol. 32, # 5 p. 1423 - 1428

14161-11-63,4,5-三氯哒嗪+

7664-41-7氨气

89180-50-7+

53180-76-04-氨基-3,5-二氯哒嗪

参考文献

Kuraishi
Pharmaceutical Bulletin, 1956 , vol. 4, p. 497

14161-11-63,4,5-三氯哒嗪

20744-39-24-氨基哒嗪

参考文献

GLAXO GROUP LIMITED; GLAXOSMITHKLINE (CHINA) RandD COMPANY LIMITED; NICHOLS, Paula Louise; EATHERTON, Andrew John; BAMBOROUGH, Paul; JANDU, Karamjit Singh; PHILPS, Oliver James; ANDREOTTI, Daniele
Patent: WO2011/38572 A1, 2011 ;
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WO 2011/038572 A1