N-氧代-4-硝基-2，2’联吡啶合成路线 （共 16 条）
反应条件
sulfuric acid; potassium nitrate T=80°C; 30 h;
参考文献
Zalas; Gierczyk; Klein; Siuzdak; Pedzinski; Luczak
Polyhedron, 2014 , vol. 67, p. 381 - 387
反应条件
tri-tert-butyl phosphine; palladium diacetate; potassium carbonate in toluene T=120°C; 24 h; Inert atmosphere;
参考文献
Duric, Sasa; Tzschucke, C. Christoph
Organic Letters, 2011 , vol. 13, # 9 p. 2310 - 2313
反应条件
1: 13.48 g / magnesium monoperoxyphthalate / ethanol / 5 h / Heating 2: 49 percent / HNO3; H2SO4 / 31 h / 100 °C View Scheme
参考文献
Trecourt, Francois; Gervais, Bruno; Mongin, Olivier; Gal, Catherine Le; Mongin, Florence; Queguiner, Guy
Journal of Organic Chemistry, 1998 , vol. 63, # 9 p. 2892 - 2897
参考文献
FMC Corporation
Patent: US4808722 A1, 1989 ;
反应条件
potassium phosphate; tri-tert-butyl phosphine; palladium diacetate in toluene T=120°C; 24 h; Inert atmosphereGlovebox;
参考文献
Duric, Sasa; Sypaseuth, Fanni D.; Hoof, Santina; Svensson, Emma; Tzschucke, C. Christoph
Chemistry - A European Journal, 2013 , vol. 19, # 51 p. 17456 - 17463
反应条件
acetyl-bromide in acetic acid Bromination; 9 h; reflux;
参考文献
Mizuno, Toshihisa; Takeuchi, Masayuki; Hamachi, Itaru; Nakashima, Kazuaki; Shinkai, Seiji
Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 10 p. 2281 - 2288
反应条件
acetyl-bromide; acetic acid 4 h; Inert atmosphereReflux;
参考文献
Kodama, Koichi; Kobayashi, Akinori; Hirose, Takuji
Tetrahedron Letters, 2013 , vol. 54, # 40 p. 5514 - 5517
反应条件
sodium tetrahydroborate; palladium on activated charcoal in methanol
参考文献
Zhou, Zhiguo; Sarova, Ginka H.; Zhang, Sheng; Ou, Zhongping; Tat, Fatma T.; Kadish, Karl M.; Echegoyen, Luis; Guldi, Dirk M.; Schuster, David I.; Wilson, Stephen R.
Chemistry - A European Journal, 2006 , vol. 12, # 16 p. 4241 - 4248
反应条件
1.1: 89 percent / Acetyl bromide / acetic acid / 9 h / reflux 2.1: 50 percent / PBr3 / CHCl3 / 4 h / reflux 3.1: diethyl ether; hexane / 0.5 h / -110 - -100 °C 3.2: 52 percent / diethyl ether; hexane / 1 h / -110 - -100 °C View Scheme
参考文献
Mizuno, Toshihisa; Takeuchi, Masayuki; Hamachi, Itaru; Nakashima, Kazuaki; Shinkai, Seiji
Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 10 p. 2281 - 2288
反应条件
1.1: 88 percent / methanol / 0.5 h / 40 °C 2.1: LTMP / tetrahydrofuran / 1.5 h / -70 °C 2.2: 94 percent / I2 / tetrahydrofuran / 1 h / -70 °C 3.1: 64 percent / PBr3 / CHCl3 / 0.75 h / Heating View Scheme
参考文献
Trecourt, Francois; Gervais, Bruno; Mongin, Olivier; Gal, Catherine Le; Mongin, Florence; Queguiner, Guy
Journal of Organic Chemistry, 1998 , vol. 63, # 9 p. 2892 - 2897
