2-丁基-3-(4-羟基苯甲酰基)-5-硝基苯并呋喃合成路线 （共 24 条）
反应条件
1.1: potassium carbonate / butanone / 0.5 h / 20 °C 1.2: 12 h / 78 - 82 °C 2.1: hydrogen / palladium 10 on activated carbon / ethyl acetate / 25 - 35 °C 3.1: triethylamine / dichloromethane / 0.5 h / 20 °C View Scheme
参考文献
Mahender; Saravanan; Sridhar; Chandrashekar; Kumar, L. Jaydeep; Jayashree; Bandichhor, Rakeshwar
Organic Process Research and Development, 2014 , vol. 18, # 1 p. 157 - 162
反应条件
1.1: potassium carbonate / butanone / 0.5 h / 20 °C 1.2: 12 h / 78 - 82 °C 2.1: hydrogen / palladium 10 on activated carbon / ethyl acetate / 25 - 35 °C View Scheme
反应条件
1: 2-n-butyl 3-(4-hydroxy benzoyl)-5-nitro benzofuran With potassium carbonate in acetonitrile 0.5 h; 2: 1-chloro-3-(di-n-butylamino)-propane in acetonitrile Reflux;
参考文献
USV Limited, B.S.D. Marg
Patent: US2012/108828 A1, 2012 ;
Location in patent: Page/Page column 6; 7 ;
反应条件
1.1: potassium carbonate / butanone / 20 h / 85 °C 1.3: 0.5 h / 25 - 65 °C 2.1: potassium carbonate / toluene; water View Scheme
参考文献
CADILA HEALTHCARE LIMITED; DWIVEDI, Shriprakash, Dhar; PATEL, Vipul, Kantibhai; PANDYA, Jayesh, Mohanlal
Patent: WO2012/32545 A1, 2012 ;
