1: 3-lt;(tert-butyldimethylsilyl)oxygt;-2-pyridone With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.333333 h; 2: p-toluenesulfonyl chloride in tetrahydrofuran; hexane T=-78 - 20°C; 1 h;

1.1: MeLi / diethyl ether / 2 h / 0 °C 1.2: 82 percent / diethyl ether / 30 h / 23 °C 2.1: 98 percent / BF3*OEt2 / CH2Cl2 / 24 h / 23 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '103853', constants.ctx, '0')">1H-imidazole</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605365', constants.ctx, '0')">N,N-dimethyl-formamide</a> <br />T=20&deg;C;&nbsp;&nbsp;Inert atmosphere;&nbsp;<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '103853', constants.ctx, '0')">1H-imidazole</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605365', constants.ctx, '0')">N,N-dimethyl-formamide</a> <br />T=23&deg;C;&nbsp;<br /> &nbsp;