甲基4-甲氧基-2-氧代-3-环戊烯-1-羧酸酯合成路线 （共 7 条）
反应条件
sodium methylate in methanol T=60°C; 3 h;
参考文献
Fuchs; McGarrity
Synthesis, 1992 , # 4 p. 373 - 374
反应条件
1: 3-methoxycyclopent-2-en-1-one With lithium hexamethyldisilazane in tetrahydrofuran T=-50°C; 0.5 h; 2: methoxycarbonyl cyanide in tetrahydrofuran T=-50 - 20°C; 2.5 h; Further stages.;
参考文献
Liang, Huan; Schule, Arnaud; Vors, Jean-Pierre; Ciufolini, Marco A.
Organic Letters, 2007 , vol. 9, # 21 p. 4119 - 4122
反应条件
lithium diisopropyl amide T=-78°C;
参考文献
Boschelli; Smith III; Stringer; et al.
Tetrahedron Letters, 1981 , vol. 22, # 44 p. 4385 - 4388
反应条件
1.1: 80 percent / TiCl4 2.1: LHMDS / tetrahydrofuran / 0.5 h / -50 °C 2.2: 52 percent / tetrahydrofuran / 2.5 h / -50 - 20 °C View Scheme
参考文献
Liang, Huan; Schule, Arnaud; Vors, Jean-Pierre; Ciufolini, Marco A.
Organic Letters, 2007 , vol. 9, # 21 p. 4119 - 4122
反应条件
lithium diisopropyl amide 1.) tetrahydrofuran, -70 deg C, 2.) tetrahydrofuran; Yield given. Multistep reaction;
参考文献
Irie, Hiroshi; Katakawa, Jun'ichi; Tomita, Masako; Mizuno, Yukio
Chemistry Letters, 1981 , p. 637 - 640
反应条件
sulfuric acid T=100°C; 2 h;
参考文献
Fuchs; McGarrity
Synthesis, 1992 , # 4 p. 373 - 374
反应条件
sodium hexamethyldisilazane; (camphorylsulfonyl)oxaziridine ((+)-7b5) in tetrahydrofuran
T=-78 - 20°C; Mechanism;
参考文献
Chen, Bang-Chi; Weismiller, Michael C.; Davis, Franklin A.; Boschelli, Diane; Empfield, James R.; Smith, Amos B.
Tetrahedron, 1991 , vol. 47, # 2 p. 173 - 182
