1-(叔丁氧基羰基)-3-吡咯烷甲基-甲磺酸酯合成路线 （共 3 条）
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane T=0 - 20°C;
参考文献
MERCK SERONO S.A.; SWINNEN, Dominique; JORAND-LEBRUN, Catherine; GRIPPI-VALLOTTON, Tania; GERBER, Patrick; GONZALEZ, Jerome; SHAW, Jeffrey; JEYAPRAKASHNARAYANAN, Seenisamy
Patent: WO2010/100144 A1, 2010 ;
Location in patent: Page/Page column 145 ;
WO 2010/100144 A1
反应条件
1: 77 percent / NaBH4 / tetrahydrofuran; methanol / 1 h / Heating 2: Et3N / tetrahydrofuran / 0.67 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 44, # 1 p. 94 - 104
反应条件
1: NaN3 / dimethylsulfoxide / 5 h / 100 °C 2: H2 / 10 percent Pd/C / methanol; CHCl3 / 16 h / 20 °C / 760 Torr View Scheme
参考文献
Falgueyret; Oballa; Okamoto; Wesolowski; Aubin; Rydzewski; Prasit; Riendeau; Rodan; Percival
Journal of Medicinal Chemistry, 2001 , vol. 44, # 1 p. 94 - 104
