sodium hydroxide; sodium tetrahydroborate; sodium hydrogencarbonate 1.) H2O, 50-55 deg C, 2.5 h, pH 8.3, 2.) 25 deg, 1 h.; Yield given. Multistep reaction;

1: 79 percent / tBuOK / dimethylformamide / 11 h / 115 °C 2: 1.) NaOH, 2.) HCl / 1.) EtOH, H2O, 25 deg C, 4 h, 2.) H2O, pH 3 3: 1.) NaBH4, NaOH, 2.) NaHCO3 / 1.) H2O, 50-55 deg C, 2.5 h, pH 8.3, 2.) 25 deg, 1 h. View Scheme

1: 82 percent / Py*HCl / 10 h / 210 °C 2: 79 percent / tBuOK / dimethylformamide / 11 h / 115 °C 3: 1.) NaOH, 2.) HCl / 1.) EtOH, H2O, 25 deg C, 4 h, 2.) H2O, pH 3 4: 1.) NaBH4, NaOH, 2.) NaHCO3 / 1.) H2O, 50-55 deg C, 2.5 h, pH 8.3, 2.) 25 deg, 1 h. View Scheme

1: 85 percent / AlCl3 / CS2 / 4 h / 25 °C 2: 82 percent / Py*HCl / 10 h / 210 °C 3: 79 percent / tBuOK / dimethylformamide / 11 h / 115 °C 4: 1.) NaOH, 2.) HCl / 1.) EtOH, H2O, 25 deg C, 4 h, 2.) H2O, pH 3 5: 1.) NaBH4, NaOH, 2.) NaHCO3 / 1.) H2O, 50-55 deg C, 2.5 h, pH 8.3, 2.) 25 deg, 1 h. View Scheme

1: 85 percent / AlCl3 / CS2 / 4 h / 25 °C 2: 82 percent / Py*HCl / 10 h / 210 °C 3: 79 percent / tBuOK / dimethylformamide / 11 h / 115 °C 4: 1.) NaOH, 2.) HCl / 1.) EtOH, H2O, 25 deg C, 4 h, 2.) H2O, pH 3 5: 1.) NaBH4, NaOH, 2.) NaHCO3 / 1.) H2O, 50-55 deg C, 2.5 h, pH 8.3, 2.) 25 deg, 1 h. View Scheme

1: 1.) NaOH, 2.) HCl / 1.) EtOH, H2O, 25 deg C, 4 h, 2.) H2O, pH 3 2: 1.) NaBH4, NaOH, 2.) NaHCO3 / 1.) H2O, 50-55 deg C, 2.5 h, pH 8.3, 2.) 25 deg, 1 h. View Scheme