4-氯-DL-苯基丙氨酸甲酯 盐酸盐合成路线 （共 6 条）
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in tetrahydrofuran P=760 Torr; 4 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 61, # 19 p. 6581 - 6586
反应条件
hydrogenchloride T=0°C;
参考文献
Li, Xun; Wang, Junli; Zhang, Lei; Xu, Wenfang
Archiv der Pharmazie, 2011 , vol. 344, # 8 p. 494 - 504
反应条件
1: 95 percent / p-TsOH / 8 h / Heating 2: H2, 5 N HCl / Pd/C / tetrahydrofuran / 4 h / 760 Torr / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 61, # 19 p. 6581 - 6586
反应条件
thionyl chloride T=0 - 20°C;
参考文献
Journal of Peptide Science, , vol. 18, # 6 p. 418 - 426
反应条件
1: ammonia / methanol / 0 °C 2: PLP; cobalt(II) chloride / aq. buffer / 36 h / 40 °C / pH 7.0 / |Enzymatic reaction View Scheme
参考文献
Yasukawa, Kazuyuki; Asano, Yasuhisa
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 17 p. 3327 - 3332
反应条件
1: ammonia / methanol / 0 °C 2: PLP; cobalt(II) chloride / aq. buffer / 36 h / 40 °C / pH 7.0 / |Enzymatic reaction View Scheme
参考文献
Yasukawa, Kazuyuki; Asano, Yasuhisa
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 17 p. 3327 - 3332
