2-((((9H-芴-9-基)甲氧基)羰基)(苄基)氨基)乙酸合成路线 （共 6 条）
反应条件
sodium hydrogencarbonate in 1,4-dioxane T=20°C;
参考文献
Weber, Dirk; Berger, Claudia; Eickelmann, Peter; Antel, Jochen; Kessler, Horst
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1918 - 1930
反应条件
1: NaOH, H2O / dioxane; methanol / 0.5 h / Ambient temperature 2: HCl, H2O, TEA / acetonitrile / 0.5 h View Scheme
参考文献
Chemistry - A European Journal, , vol. 4, # 8 p. 1570 - 1580
反应条件
1: 97 percent / tetrahydrofuran / 2.5 h / Ambient temperature 2: NaOH, H2O / dioxane; methanol / 0.5 h / Ambient temperature 3: HCl, H2O, TEA / acetonitrile / 0.5 h View Scheme
参考文献
Chemistry - A European Journal, , vol. 4, # 8 p. 1570 - 1580
反应条件
hydrogenchloride; TEA; water in acetonitrile 0.5 h; Yield given;
参考文献
Chemistry - A European Journal, , vol. 4, # 8 p. 1570 - 1580
反应条件
in water; acetonitrile T=20°C; 0.5 h;
参考文献
Jahnsen, Rasmus D.; Frimodt-Moller, Niels; Franzyk, Henrik
Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7253 - 7261
反应条件
solid phase synthesis; Yield given. Multistep reaction;
参考文献
Boeijen, Astrid; Liskamp, Rob M.J.
Tetrahedron Letters, 1998 , vol. 39, # 21 p. 3589 - 3592
