2-甲基-1,4-苯二甲酸二甲酯合成路线 （共 5 条）
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; tetrakis(triphenylphosphine) palladium(0) T=65°C; 16 h;
参考文献
WO2009/126863 A2, ;
Page/Page column 140-141 ;
反应条件
thionyl chloride 2 h; Heating / reflux;
参考文献
ALANTOS PHARMACEUTICALS, INC.
Patent: WO2006/116157 A2, 2006 ;
Location in patent: Page/Page column 77-78 ;
WO 2006/116157 A2
反应条件
sulfuric acid in methanol
反应条件
in tetrahydrofuran; diethyl ether
参考文献
Eichinger, Karl; Berbalk, Hans; Schuster, Rudolf
Journal of Chemical Research, Miniprint, 1982 , # 8 p. 2072 - 2081
反应条件
1: 50 percent / 28percent HNO3 / 20 h / Heating 2: 84.1 percent / tetrahydrofuran; diethyl ether View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 8 p. 2072 - 2081
