哌嗪二盐酸盐合成路线

参考文献

UCB, S.A.
Patent: US6140501 A1, 2000 ;

参考文献

Srivastava, Priyanka; Ali, Rashid; Razi, Syed S.; Shahid, Mohammad; Patnaik, Satyakam; Misra, Arvind
Tetrahedron Letters, 2013 , vol. 54, # 28 p. 3688 - 3693

110-85-0哌嗪+

52200-48-33-溴-2-氯吡啶+

142-64-3哌嗪二盐酸盐

87394-56-71-(3-溴吡啶-2-基)哌嗪

参考文献

WO2008/141020 A1, ;

Page/Page column 48 ;
WO 2008/141020 A1

27064-94-4氯代双(4-氟苯基甲烷)+

142-64-3哌嗪二盐酸盐

27469-60-94,4'-二氟苯甲哌嗪

参考文献

Santhoshi, Amlipur; Kumar, Singam Naveen; Sujitha, Pombala; Poornachandra, Yedla; Sadhu, Partha Sarathi; Kumar, C. Ganesh; Rao, Vaidya Jayathirtha
Medicinal Chemistry Research, 2014 , vol. 23, # 6 p. 3207 - 3219

142-64-3哌嗪二盐酸盐

110-85-0哌嗪

参考文献

Poppenberg; Mayer
Patent: DE657979 , 1936 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, 24552

3933-94-64-苯氧基联苯+

142-64-3哌嗪二盐酸盐

110-85-0哌嗪

参考文献

Dow Chem.Co.
Patent: US2843590 , 1956 ;

2417-72-34-溴甲基苯甲酸甲酯+

142-64-3哌嗪二盐酸盐+

142-63-2哌嗪(六水)

86620-81-7伊马替尼中间体4-哌啶甲基苯甲酸甲酯

参考文献

Boehringer Mannheim GmbH
Patent: US4616086 A1, 1986 ;

142-64-3哌嗪二盐酸盐

290-37-9吡嗪

参考文献

Stoehr
Journal fuer Praktische Chemie (Leipzig), 1893 , vol. <2> 47, p. 453
Journal fuer Praktische Chemie (Leipzig), 1893 , vol. 48, p. 21

110-85-0哌嗪+

142-64-3哌嗪二盐酸盐+

824-94-24-甲氧基氯苄

21867-69-61-(4-甲氧苄基)哌嗪

参考文献

Cunico, Wilson; Gomes, Claudia R.B.; Moreth, Marcele; Manhanini, Diogo P.; Figueiredo, Isabela H.; Penido, Carmen; Henriques, Maria G.M.O.; Varotti, Fernando P.; Krettli, Antoniana U.
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 3 p. 1363 - 1368

110-85-0哌嗪+

142-64-3哌嗪二盐酸盐+

100-14-11-(氯甲基)-4-硝基苯

58198-49-51-[(4-硝基苯基)甲基]哌嗪

参考文献

Cunico, Wilson; Gomes, Claudia R.B.; Moreth, Marcele; Manhanini, Diogo P.; Figueiredo, Isabela H.; Penido, Carmen; Henriques, Maria G.M.O.; Varotti, Fernando P.; Krettli, Antoniana U.
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 3 p. 1363 - 1368