1-[(乙酰基硫代)甲基]-环丙烷乙酸 甲酯合成路线 （共 5 条）
反应条件
sodium hydrogencarbonate; triethylamine in dichloromethane; N,N-dimethyl-formamide
参考文献
Merck Frosst Canada, Inc.
Patent: US5565473 A1, 1996 ;
反应条件
sodium hydrogencarbonate; triethylamine in dichloromethane; N,N-dimethyl-formamide
参考文献
Merck Frosst Canada, Inc.
Patent: US5212180 A1, 1993 ;
US 5212180 A
反应条件
sodium hydrogencarbonate in dichloromethane; N,N-dimethyl-formamide
参考文献
Merck Frosst Canada, Inc.
Patent: US5428033 A1, 1995 ;
US 5428033 A
反应条件
1.1: caesium carbonate / methanol / 20 °C / Inert atmosphere 2.1: 1-methyl-pyrrolidin-2-one / 0 - 20 °C / Inert atmosphere 3.1: sodium hydroxide; water / 2-methyl tetrahydrofuran; methanol / 2 h / 70 - 80 °C / Inert atmosphere 3.2: 20 °C View Scheme
参考文献
RICHTER GEDEON NYRT.; BODI, Jozsef; FARAGO, Janos; SZOeKE, Katalin; UJVARI, Viktor; TEMESVARI, Krisztina; ARANYI, Antal; SANTA, Zsuzsanna; NAGY, Melinda Magdolna
Patent: WO2012/20271 A1, 2012 ;
反应条件
1.1: caesium carbonate / methanol / 20 °C / Inert atmosphere 2.1: 1-methyl-pyrrolidin-2-one / 0 - 20 °C / Inert atmosphere 3.1: sodium hydroxide; water / 2-methyl tetrahydrofuran; methanol / 2 h / 70 - 80 °C / Inert atmosphere 3.2: 20 °C 4.1: potassium dihydrogenphosphate / dichloromethane; water / 0.25 h / 20 °C 4.2: 0.25 h View Scheme
参考文献
RICHTER GEDEON NYRT.; BODI, Jozsef; FARAGO, Janos; SZOeKE, Katalin; UJVARI, Viktor; TEMESVARI, Krisztina; ARANYI, Antal; SANTA, Zsuzsanna; NAGY, Melinda Magdolna
Patent: WO2012/20271 A1, 2012 ;
