(S)-2-(氰基甲基)吡咯烷-1-甲酸叔丁酯合成路线 （共 12 条）
反应条件
1: 84 percent / K2CO3 / tetrahydrofuran; H2O / 20 °C / pH 9 2: 100 percent / Et3N / CH2Cl2 / 0 °C 3: 78 percent / dimethylformamide / 100 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 3 p. 342 - 345
反应条件
ammonia; hydrogen; dihydrogen hexachloroplatinate; nickel in methanol; water P=2068.65 Torr; 24 h;
参考文献
JAMES BLACK FOUNDATION LIMITED
Patent: EP1056733 B1, 2004 ;
Location in patent: Page 34-35 ;
