(R)-(-)-N-苯甲基-2-苯基甘氨酸醇合成路线 （共 32 条）
反应条件
in tetrahydrofuran T=-40 - 20°C; 6 h;
参考文献
Tetrahedron Letters, , vol. 46, # 28 p. 4761 - 4764
反应条件
in tetrahydrofuran T=-78 - 20°C;
参考文献
Tetrahedron Letters, , vol. 46, # 28 p. 4761 - 4764
反应条件
1: methanol / 1 h 2: NaBH4 / methanol / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 20 p. 6423 - 6426
反应条件
1: APTS / toluene / 2 h / Heating 2: 50 percent / tetrahydrofuran / -78 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 28 p. 4761 - 4764
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 24 h; Heating;
参考文献
Maury, Catherine; Gharbaoui, Tawfik; Royer, Jacques; Husson, Henri-Philippe
Journal of Organic Chemistry, 1996 , vol. 61, # 11 p. 3687 - 3693
反应条件
trifluoroacetic acid in dichloromethane 1.5 h; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 30, # 34 p. 4539 - 4542
反应条件
1: toluene / 2 h / Heating 2: HIO4 / methanol / 1 h / 0 °C 3: NaBH4 / methanol / 1 h / Ambient temperature 4: CF3CO2H / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 30, # 34 p. 4539 - 4542
反应条件
1: tetrahydrofuran / 2 h / -60 °C 2: concd. HCl / methanol / 1 h / Heating 3: toluene / 2 h / Heating 4: HIO4 / methanol / 1 h / 0 °C 5: NaBH4 / methanol / 1 h / Ambient temperature 6: CF3CO2H / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 30, # 34 p. 4539 - 4542
反应条件
1: HIO4 / methanol / 1 h / 0 °C 2: NaBH4 / methanol / 1 h / Ambient temperature 3: CF3CO2H / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 30, # 34 p. 4539 - 4542
反应条件
1: concd. HCl / methanol / 1 h / Heating 2: toluene / 2 h / Heating 3: HIO4 / methanol / 1 h / 0 °C 4: NaBH4 / methanol / 1 h / Ambient temperature 5: CF3CO2H / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 30, # 34 p. 4539 - 4542
