6-(三氟甲基)-1-苯并噻吩-2-羧酸合成路线 （共 2 条）
反应条件
1: With methanol; lithium hydroxide; water in tetrahydrofuran 1 h; 2: With hydrogenchloride in water
参考文献
WO2007/61764 A2, ;
Page/Page column 84 ;
WO 2007/061764 A2
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 140 °C 2: water; lithium hydroxide hydrate / methanol / 2 h / 75 °C View Scheme
