1: With bis(trichloromethyl) carbonate in dichloromethane T=0°C; 2: With N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 4 h; Heating / reflux;
参考文献
IRM LLC; NOVARTIS, AG
Patent: WO2007/38669 A2, 2007 ;
Location in patent: Page/Page column 170 ;
Chacon, Almary; Masterson, Douglas S.; Yin, Huiyong; Liebler, Daniel C.; Porter, Ned A.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 18 p. 6213 - 6222
