2-氯-4,6-二甲基-3-氰基吡啶合成路线 （共 33 条）
反应条件
trichlorophosphate 3 h; Heating;
参考文献
Klunder, Janice M.; Hargrave, Karl D.; West, MaryAnn; Cullen, Ernest; Pal, Kollol; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1887 - 1897
反应条件
triethylamine; trichlorophosphate in acetonitrile 2 h; Reflux;
参考文献
Waly, Mohamed A.; El-Hawary, Ibrahim I.; Hamama, Wafaa S.; Zoorob, Hanafi H.
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # SUPPL.1 p. E12-E17
参考文献
Dmitrieva; Dyadyuchenko; Strelkov; Kaigorodova
Chemistry of Heterocyclic Compounds, 2009 , vol. 45, # 9 p. 1047 - 1052
反应条件
1: piperidine / ethanol / 3 h / |Reflux 2: trichlorophosphate; triethylamine / acetonitrile / 2 h / |Reflux View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 50, # SUPPL.1 p. E12-E17
反应条件
hydrogenchloride; chlorine T=0°C; 1 h;
参考文献
Journal of the Indian Chemical Society, , vol. 73, # 2-3 p. 141 - 143
反应条件
1: 76 percent / H2SO4 / 3 h / Heating 2: conc. aq. HCl, Cl2 / 1 h / 0 °C View Scheme
参考文献
Journal of the Indian Chemical Society, , vol. 73, # 2-3 p. 141 - 143
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide T=120°C; 6 h; sealed tube;
参考文献
Sakamoto, Takao; Kondo, Yoshinori; Yamanaka, Hiroshi
Chemical & Pharmaceutical Bulletin, 1986 , vol. 34, p. 2362 - 2368
反应条件
ammonia in ethanol T=160°C; 24 h; Sealed tubeAutoclave;
参考文献
Vallerini, Gian Paolo; Amori, Laura; Beato, Claudia; Tararina, Margarita; Wang, Xiao-Dan; Schwarcz, Robert; Costantino, Gabriele
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9482 - 9495
反应条件
in ethanol 10 h; Heating;
参考文献
Lynch; Khan; Teo; Pedrotti
Canadian Journal of Chemistry, 1988 , vol. 66, # 3 p. 420-428
反应条件
hydrazine hydrate in ethanol 4 h; Heating;
参考文献
El-Dean, A M Kamal; Geies, A A; Mohamed, Th A; Atalla, A A
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1991 , vol. 30, # 9 p. 878 - 882
