2-氯-4,6-二甲基-3-氰基吡啶合成路线 (共 33 条)
反应条件
1.1: thiourea / butan-1-ol / 4 h / 118 °C
2.1: sulfuric acid / 4 h / 100 °C
2.2: pH 5 - 6
View Scheme
参考文献
CHANG, Zee-Fen; HU, Chun-Mei; FANG, Jim-Min; YEH, Ming-Tyng
Patent: WO2012/72019 A1, 2012 ;
WO 2012/072019 A1
反应条件
sodium ethanolate in ethanol
参考文献
Shevdov,V.I. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1979 , vol. 15, p. 1070 - 1074
Khimiya Geterotsiklicheskikh Soedinenii, 1979 , vol. 15, p. 1331 - 1335
反应条件
1: Na2CO3
2: POCl3
View Scheme
参考文献
Shevdov,V.I. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1979 , vol. 15, p. 1070 - 1074
Khimiya Geterotsiklicheskikh Soedinenii, 1979 , vol. 15, p. 1331 - 1335