2-氨基-4-甲基-5-噻唑甲胺溴酸盐合成路线 （共 4 条）
反应条件
hydrogen bromide 5 h; Heating;
参考文献
Eriks; Van der Goot; Sterk; Timmerman
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3239 - 3246
反应条件
1: 62.8 percent / K2CO3, KI / dimethylformamide / 3 h / 110 °C 2: 63.5 percent / Br2 / CCl4 / 3 h / Ambient temperature 3: 55.3 percent / dimethylformamide / 3 h / 120 °C 4: 75.2 percent / 30percent aq. HBr / 5 h / Heating View Scheme
参考文献
Eriks; Van der Goot; Sterk; Timmerman
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3239 - 3246
反应条件
1: 63.5 percent / Br2 / CCl4 / 3 h / Ambient temperature 2: 55.3 percent / dimethylformamide / 3 h / 120 °C 3: 75.2 percent / 30percent aq. HBr / 5 h / Heating View Scheme
参考文献
Eriks; Van der Goot; Sterk; Timmerman
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3239 - 3246
反应条件
1: 55.3 percent / dimethylformamide / 3 h / 120 °C 2: 75.2 percent / 30percent aq. HBr / 5 h / Heating View Scheme
参考文献
Eriks; Van der Goot; Sterk; Timmerman
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3239 - 3246
