1-[4'-(三氟甲基)-4-联苯基]乙酮合成路线 (共 18 条)
反应条件
tripotassium phosphate monohydrate; palladium diacetate; α,α'-bis(di-t-butylphosphino)-o-xylene in tetrahydrofuran T=20°C; Suzuki-Miyaura cross-coupling reaction; 48 h; Inert atmosphere;
参考文献
Tetrahedron Letters, , vol. 50, # 20 p. 2342 - 2346
反应条件
tetrabutylammomium bromide; palladium diacetate; potassium carbonate in water T=60°C; 2 h; Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 18 p. 6364 - 6374
反应条件
potassium fluoride; lithium hydroxide; n-butyllithium; triphenylphosphine in 1,4-dioxane; hexane T=180°C; Suzuki-Miyaura coupling; 1.1 h; Inert atmosphereMicrowave irradiation;
参考文献
Organic Letters, , vol. 10, # 19 p. 4279 - 4282
反应条件
sodium hydroxide; dichloro bis(acetonitrile) palladium(II) in 1,4-dioxane T=80°C; 4 h;
参考文献
Synthesis, , # 15 p. 2231 - 2233
反应条件
[Pd(N3)(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)(N,N'-dimethylbenzylamine(-H))]; caesium carbonate in ethanol T=80°C; Suzuki-Miyaura Coupling; 1 h; Inert atmosphereHeating; Catalytic behavior;
参考文献
European Journal of Inorganic Chemistry, , # 36 p. 6011 - 6017
反应条件
CM-phos; tetrabutyl ammonium fluoride; palladium diacetate; acetic acid in tert-butyl alcohol T=90°C; Hiyama cross-coupling; 16 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 11, # 2 p. 317 - 320
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; water T=20°C; 12 h;
参考文献
European Journal of Organic Chemistry, , # 13 p. 2545 - 2554
反应条件
palladium diacetate in 1,4-dioxane
反应条件
C16H16Cl2N2O4Pd2; tetrabutylammomium bromide; potassium carbonate in water 8 h; RefluxDarknessInert atmosphere;
参考文献
Organic Letters, , vol. 10, # 21 p. 5011 - 5014
反应条件
potassium fluoride; potassium carbonate in water T=100°C; Suzuki-Miyaura coupling; 8 h;
参考文献
Green Chemistry, , vol. 12, # 1 p. 150 - 158