1: (1E)-iodo-(3S)-(tetrahydro-2H-pyran-2-yloxy)-1-octene With 1-pentynyl-copper; n-butyllithium; tris-(dimethylamino)-phosphine in diethyl ether; hexane T=-70°C; 0.5 h; 2: (R)-1-(3-(tert-butyldimethylsilyloxy)benzyl)-5-oxo-3-(tetrahydro-2H-pyran-2-yloxy)-cyclopentene in diethyl ether; hexane T=-70°C; 0.5 h;