(R)-(+)-4-叔丁基-2-噁唑烷酮合成路线 （共 11 条）
反应条件
sodium hydroxide in water; acetic acid
参考文献
Degussa Aktiengesellschaft
Patent: US5723667 A1, 1998 ;
反应条件
thionyl chloride in tetrahydrofuran T=0°C; 3 h;
参考文献
Matsunaga, Hirofumi; Ishizuka, Tadao; Kunieda, Takehisa
Tetrahedron, 1997 , vol. 53, # 4 p. 1275 - 1294
反应条件
potassium carbonate in toluene 3 h; Heating;
参考文献
Spino, Claude; Tremblay, Marie-Claude; Gobdout, Cedrickx
Organic Letters, 2004 , vol. 6, # 16 p. 2801 - 2804
反应条件
diphenyl phosphoryl azide; triethylamine in xylene 12 h; Heating;
参考文献
Takacs; Jaber; Vellekoop
Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2742 - 2748
反应条件
1.1: DPPA; Et3N / toluene / 1 h / Heating 1.2: 76 percent / methanol / 1 h / Heating 2.1: O3; sudan III / CH2Cl2 / -78 °C 2.2: 81 percent / NaBH4 / CH2Cl2; methanol / 15 h / 20 °C 3.1: 73 percent / K2CO3 / toluene / 3 h / Heating View Scheme
参考文献
Organic Letters, , vol. 6, # 16 p. 2801 - 2804
反应条件
1.1: O3; sudan III / CH2Cl2 / -78 °C 1.2: 81 percent / NaBH4 / CH2Cl2; methanol / 15 h / 20 °C 2.1: 73 percent / K2CO3 / toluene / 3 h / Heating View Scheme
参考文献
Organic Letters, , vol. 6, # 16 p. 2801 - 2804
反应条件
1.1: 100 percent / Jones reagent / acetone / 2 h / 0 °C 2.1: DPPA; Et3N / toluene / 1 h / Heating 2.2: 76 percent / methanol / 1 h / Heating 3.1: O3; sudan III / CH2Cl2 / -78 °C 3.2: 81 percent / NaBH4 / CH2Cl2; methanol / 15 h / 20 °C 4.1: 73 percent / K2CO3 / toluene / 3 h / Heating View Scheme
参考文献
Organic Letters, , vol. 6, # 16 p. 2801 - 2804
反应条件
lithium borohydride in tetrahydrofuran; methanol Ambient temperature;
参考文献
Chemistry Letters, , # 6 p. 991 - 994
参考文献
Chemistry Letters, , # 6 p. 991 - 994
反应条件
1: Et3N, DMAP / CH2Cl2 / 9 h / Ambient temperature 2: 78 percent / NaBH4, MeOH / ethanol / 24 h / Ambient temperature 3: 100 percent / SOCl2 / tetrahydrofuran / 3 h / 0 °C View Scheme
参考文献
Tetrahedron, , vol. 53, # 4 p. 1275 - 1294
