3-(4-氯苯基)-5-(三氟甲基)-1H-吡唑合成路线 (共 3 条)
反应条件
1: sodium acetate / N,N-dimethyl-formamide / 20 °C / |Schlenk technique 2: N,N-dimethyl-formamide; toluene; water / 5 h / 45 °C / |Schlenk technique View Scheme
参考文献
Li, Feng; Nie, Jing; Sun, Long; Zheng, Yan; Ma, Jun-An
Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6255 - 6258
反应条件
in water; N,N-dimethyl-formamide; toluene T=45°C; 5 h; Schlenk technique; regioselective reaction;
参考文献
Li, Feng; Nie, Jing; Sun, Long; Zheng, Yan; Ma, Jun-An
Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6255 - 6258
反应条件
sulfuric acid in ethanol 5 h; Reflux;
参考文献
Aggarwal, Ranjana; Kumar, Rajiv; Singh, Shiv P.
Journal of Fluorine Chemistry, 2009 , vol. 130, # 10 p. 886 - 893