5'-O-三苯甲基-2'-脱氧尿苷合成路线 （共 19 条）
参考文献
Nguyen, Corinne; Kasinathan, Ganasan; Leal-Cortijo, Isabel; Musso-Buendia, Alexander; Kaiser, Marcel; Brun, Reto; Ruiz-Perez, Luis M.; Johansson, Nils G.; Gonzalez-Pacanowska, Dolores; Gilbert, Ian H.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 19 p. 5942 - 5954
反应条件
pyridine 2 h; Heating / reflux;
参考文献
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
Patent: EP1674104 A1, 2006 ;
Location in patent: Page/Page column 11; 19 ;
参考文献
Chatelain, Gregory; Debing, Yannick; De Burghgraeve, Tine; Zmurko, Joanna; Saudi, Milind; Rozenski, Jef; Neyts, Johan; Van Aerschot, Arthur
European Journal of Medicinal Chemistry, 2013 , vol. 65, p. 249 - 255
反应条件
copper(II) sulfate in xylene 4 h; Heating;
参考文献
Nucleosides, Nucleotides and Nucleic Acids, , vol. 27, # 8 p. 931 - 948
反应条件
copper(II) sulfate in xylene 5 h; Heating;
参考文献
Cabral, Nadia L. D.; Thiessen, Luciano Hoeltgebaum; Doboszewski, Bogdan
Nucleosides, Nucleotides and Nucleic Acids, 2008 , vol. 27, # 8 p. 931 - 948
反应条件
1: 93 percent / pyridine / 24 h / 4 °C 2: 88 percent / 1N NaOH / ethanol; H2O / 4 h / Heating 3: 91 percent / pyridine / 24 h / Ambient temperature 4: 86 percent / LiN3 / dimethylformamide / 2 h / 85 °C 5: 70 percent / 80percent acetic acid / 0.33 h / Heating 6: 86 percent / H2 / 10percent Pd/C / ethanol / 2 h / 2585.7 Torr View Scheme
参考文献
Lin; Mancini
Journal of Medicinal Chemistry, 1983 , vol. 26, # 4 p. 544 - 548
反应条件
1: 93 percent / pyridine / 24 h / 4 °C 2: 88 percent / 1N NaOH / ethanol; H2O / 4 h / Heating 3: 91 percent / pyridine / 24 h / Ambient temperature 4: 86 percent / LiN3 / dimethylformamide / 2 h / 85 °C 5: 70 percent / 80percent acetic acid / 0.33 h / Heating 6: pyridine / 24 h / 4 °C 7: thionyl chloride / CHCl3; dimethylformamide / 6 h / Heating 8: 31 percent / NH3 / methanol / 144 h / Ambient temperature 9: 65 percent / H2 / 10percent Pd/C / methanol / 2 h / 2585.7 Torr View Scheme
参考文献
Lin; Mancini
Journal of Medicinal Chemistry, 1983 , vol. 26, # 4 p. 544 - 548
反应条件
ammonium cerium(IV) nitrate; iodine; sodium hydrogencarbonate in acetonitrile 96 h; Heating / reflux;
参考文献
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
Patent: EP1674104 A1, 2006 ;
Location in patent: Page/Page column 11; 20 ;
反应条件
silica gel; trifluoroacetic acid in methanol; chloroform
参考文献
Pathak, Ashish K.; Pathak, Vibha; Seitz, Lainne E.; Tiwari, Kamal N.; Akhtar, Mohammad S.; Reynolds, Robert C
Tetrahedron Letters, 2001 , vol. 42, # 44 p. 7755 - 7757
反应条件
copper(II) sulfate in xylene 4 h; Heating;
参考文献
Nucleosides, Nucleotides and Nucleic Acids, , vol. 27, # 8 p. 931 - 948
