copper(II) sulfate in xylene 5 h; Heating;

1: 93 percent / pyridine / 24 h / 4 °C 2: 88 percent / 1N NaOH / ethanol; H2O / 4 h / Heating 3: 91 percent / pyridine / 24 h / Ambient temperature 4: 86 percent / LiN3 / dimethylformamide / 2 h / 85 °C View Scheme

1: 93 percent / pyridine / 24 h / 4 °C 2: 88 percent / 1N NaOH / ethanol; H2O / 4 h / Heating 3: 91 percent / pyridine / 24 h / Ambient temperature 4: 86 percent / LiN3 / dimethylformamide / 2 h / 85 °C 5: 70 percent / 80percent acetic acid / 0.33 h / Heating 6: pyridine / 24 h / 4 °C View Scheme

1: 93 percent / pyridine / 24 h / 4 °C 2: 88 percent / 1N NaOH / ethanol; H2O / 4 h / Heating 3: 91 percent / pyridine / 24 h / Ambient temperature 4: 86 percent / LiN3 / dimethylformamide / 2 h / 85 °C 5: 70 percent / 80percent acetic acid / 0.33 h / Heating 6: pyridine / 24 h / 4 °C 7: thionyl chloride / CHCl3; dimethylformamide / 6 h / Heating 8: 31 percent / NH3 / methanol / 144 h / Ambient temperature View Scheme

1: 93 percent / pyridine / 24 h / 4 °C 2: 88 percent / 1N NaOH / ethanol; H2O / 4 h / Heating 3: 91 percent / pyridine / 24 h / Ambient temperature 4: 86 percent / LiN3 / dimethylformamide / 2 h / 85 °C 5: 70 percent / 80percent acetic acid / 0.33 h / Heating View Scheme

pyridine T=4°C; 24 h;

1: 93 percent / pyridine / 24 h / 4 °C 2: 88 percent / 1N NaOH / ethanol; H2O / 4 h / Heating 3: 91 percent / pyridine / 24 h / Ambient temperature View Scheme

copper(II) sulfate in xylene 5 h; Heating;

copper(II) sulfate in xylene 5 h; Heating;