2-[4-(苄氧基)苯氧基]乙酸乙酯合成路线 (共 6 条)
反应条件
potassium carbonate in acetone 6 h; Heating / reflux;
参考文献
ARTESIAN THERAPEUTICS, INC.
Patent: WO2005/16885 A2, 2005 ;
Location in patent: Page/Page column 49-50 ;
WO 2005/016885 A2
反应条件
thionyl chloride in dichloromethane T=20°C; 1 h;
参考文献
Maingot, Lucie; Elbakali, Jamal; Dumont, Julie; Bosc, Damien; Cousaert, Nicolas; Urban, Agathe; Deglane, Gaelle; Villoutreix, Bruno; Nagase, Hideaki; Sperandio, Olivier; Leroux, Florence; Deprez, Benoit; Deprez-Poulain, Rebecca
European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 244 - 261
反应条件
potassium carbonate in butanone 24 h; Heating;
参考文献
Booth, Christopher J.; Gray, George W.; Toyne, Kenneth J.; Hardy, Judith
Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals, 1992 , vol. 210, p. 31 - 58
反应条件
in N,N-dimethyl-formamide
参考文献
Eli Lilly and Company
Patent: US6140352 A1, 2000 ;
US 6140352 A
反应条件
potassium hydroxide in 2-methoxy-ethanol T=100°C; 1.75 h;
参考文献
Booth, Christopher J.; Gray, George W.; Toyne, Kenneth J.; Hardy, Judith
Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals, 1992 , vol. 210, p. 31 - 58
反应条件
hydrogen; palladium on activated charcoal in tetrahydrofuran
T=20°C; P=2280 Torr; 7 h;
参考文献
Wyeth Holdings Corporation
Patent: EP1147080 B1, 2004 ;
Location in patent: Page 26 ;