N,N-二己基-2-(4-氟苯)吲哚-3-乙酰胺合成路线 （共 7 条）
反应条件
1: acetic acid / ethanol / 60 °C 2: 127 mg / KOtBu / ethanol / 20 °C View Scheme
参考文献
Opatz, Till; Ferenc, Dorota
Organic Letters, 2006 , vol. 8, # 20 p. 4473 - 4475
反应条件
1: 67 percent / zinc; acetic acid / ethanol / 1 h / 60 °C 2: acetic acid / ethanol / 60 °C 3: 127 mg / KOtBu / ethanol / 20 °C View Scheme
参考文献
Opatz, Till; Ferenc, Dorota
Organic Letters, 2006 , vol. 8, # 20 p. 4473 - 4475
反应条件
1: 94 percent / 1-hydroxybenzotriazole; DIPEA; HBTU / CH2Cl2 / 3 h / 20 °C 2: 67 percent / zinc; acetic acid / ethanol / 1 h / 60 °C 3: acetic acid / ethanol / 60 °C 4: 127 mg / KOtBu / ethanol / 20 °C View Scheme
参考文献
Kozikowski, Alan P.; Ma, Dawei; Romeo, Elena; Auta, James; Papadopoules, Vissilios; et al.
Angewandte Chemie, 1992 , vol. 104, # 8 p. 1092 - 1094
反应条件
1: 94 percent / 1-hydroxybenzotriazole; DIPEA; HBTU / CH2Cl2 / 3 h / 20 °C 2: 67 percent / zinc; acetic acid / ethanol / 1 h / 60 °C 3: acetic acid / ethanol / 60 °C 4: 127 mg / KOtBu / ethanol / 20 °C View Scheme
参考文献
Opatz, Till; Ferenc, Dorota
Organic Letters, 2006 , vol. 8, # 20 p. 4473 - 4475
反应条件
1: Et3N / tetrahydrofuran / 0.5 h / -40 deg C to -20 deg C 2: Ambient temperature 3: 0.5 h / 100 °C 4: ZnCl2 / 0.08 h / 170 °C View Scheme
参考文献
Kozikowski, Alan P.; Ma, Dawei; Romeo, Elena; Auta, James; Papadopoules, Vissilios; et al.
Angewandte Chemie, 1992 , vol. 104, # 8 p. 1092 - 1094
反应条件
1: Ambient temperature 2: 0.5 h / 100 °C 3: ZnCl2 / 0.08 h / 170 °C View Scheme
参考文献
Kozikowski, Alan P.; Ma, Dawei; Romeo, Elena; Auta, James; Papadopoules, Vissilios; et al.
Angewandte Chemie, 1992 , vol. 104, # 8 p. 1092 - 1094
反应条件
1: 0.5 h / 100 °C 2: ZnCl2 / 0.08 h / 170 °C View Scheme
参考文献
Kozikowski, Alan P.; Ma, Dawei; Romeo, Elena; Auta, James; Papadopoules, Vissilios; et al.
Angewandte Chemie, 1992 , vol. 104, # 8 p. 1092 - 1094
