反应条件
1.1: NaI / tetrahydrofuran / Heating 2.1: NaOEt / ethanol / 0.5 h 2.2: 1.25 g / ethanol / Heating 3.1: 540 mg / aq. HCl / Heating 4.1: 78 percent / NaHCO3 / H2O / 0.17 h / pH 8 5.1: 43 percent / aq. NaOH; CoCl2*6H2O; acylase I from Aspergillus melleus / aq. phosphate buffer / 39 °C / pH 7.2 View Scheme
参考文献
Kahnberg, Pia; Lucke, Andrew J.; Glenn, Matthew P.; Boyle, Glen M.; Tyndall, Joel D. A.; Parsons, Peter G.; Fairlie, David P.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7611 - 7622
