5,6-二甲氧基-1H-吲哚-3-甲醛合成路线 （共 6 条）
反应条件
trichlorophosphate T=0 - 40°C; Vilsmeier formylation;
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6270 - 6282
反应条件
1: 76 percent / methanol / -10 °C 2: 86 percent / xylene / Heating 3: 85 percent / aq. NaOH / Heating 4: 61 percent / Cu; quinoline / Heating 5: 86 percent / phosphoryl chloride / 0 - 40 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6270 - 6282
反应条件
1: 86 percent / xylene / Heating 2: 85 percent / aq. NaOH / Heating 3: 61 percent / Cu; quinoline / Heating 4: 86 percent / phosphoryl chloride / 0 - 40 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6270 - 6282
反应条件
Vilsmeier-Haack Reaction;
参考文献
WO2005/9958 A1, ;
Page 156 ;
WO 2005/009958 A1
反应条件
1: 61 percent / Cu; quinoline / Heating 2: 86 percent / phosphoryl chloride / 0 - 40 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6270 - 6282
反应条件
1: 85 percent / aq. NaOH / Heating 2: 61 percent / Cu; quinoline / Heating 3: 86 percent / phosphoryl chloride / 0 - 40 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6270 - 6282
