1-(4-硝基苯基)-5-(三氟甲基)-1H-吡唑-4-羧酸合成路线 （共 4 条）
反应条件
1: With lithium hydroxide; water in methanol T=20°C; 2 - 4 h; Heating / reflux; 2: With hydrogenchloride in water pH=1;
参考文献
Anderson, Kevin William; Fotouhi, Nader; Gillespie, Paul; Goodnow, Robert Alan; Guertin, Kevin Richard; Haynes, Nancy-Ellen; Myers, Michael Paul; Pietranico-Cole, Sherrie Lynn; Qi, Lida; Rossman, Pamela Loreen; Scott, Nathan Robert; Thakkar, Kshitij Chhabilbhai; Tilley, Jefferson Wright; Zhang, Qiang
Patent: US2007/225280 A1, 2007 ;
Location in patent: Page/Page column 18; 34 ;
US 20070225280 A1
反应条件
potassium hydroxide in ethanol 4 h; Ambient temperature;
参考文献
Okada, Etsuji; Masuda, Ryoichi; Hojo, Masaru
Heterocycles, 1992 , vol. 34, # 4 p. 791 - 798
反应条件
1: 94 percent / Et3N / acetonitrile / 1 h / Ambient temperature 2: 84 percent / sat. aq. KOH / ethanol / 4 h / Ambient temperature View Scheme
参考文献
Heterocycles, , vol. 34, # 4 p. 791 - 798
反应条件
1: 94 percent / Et3N / acetonitrile / 1 h / Ambient temperature 2: 84 percent / sat. aq. KOH / ethanol / 4 h / Ambient temperature View Scheme
参考文献
Heterocycles, , vol. 34, # 4 p. 791 - 798
