palladium diacetate; sodium t-butanolate; dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine in 1,4-dioxane T=90°C; Buchwald-Hartwig Coupling; 16 h; Inert atmosphereSchlenk technique;

1: tris-(dibenzylideneacetone)dipalladium(0); N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine; sodium t-butanolate / toluene / 110 °C / |Inert atmosphere 2: trifluoroacetic acid / dichloromethane / 2 h View Scheme