(4S)-2,5-二氧代-4-(苯基甲基)-3-恶唑烷羧酸叔丁酯合成路线 （共 7 条）
反应条件
in tetrahydrofuran T=-15°C; 144 h;
参考文献
Journal of the American Chemical Society, , vol. 123, # 50 p. 12696 - 12697
反应条件
4 A molecular sieve in diethyl ether T=-40°C; 15 h; Title compound not separated from byproducts.;
参考文献
Hang; Tian; Tang; Deng
Journal of the American Chemical Society, 2001 , vol. 123, # 50 p. 12696 - 12697
反应条件
sodium tetrahydroborate in ethylene glycol dimethyl ether; water 0.166667 h; Ambient temperature;
参考文献
Fehrentz, Jean-Alain; Califano, Jean-Christophe; Amblard, Muriel; Loffet, Albert; Martinez, Jean
Tetrahedron Letters, 1994 , vol. 35, # 4 p. 569 - 572
反应条件
4 A molecular sieve in diethyl ether T=-40°C; 15 h; Title compound not separated from byproducts.;
参考文献
Hang; Tian; Tang; Deng
Journal of the American Chemical Society, 2001 , vol. 123, # 50 p. 12696 - 12697
反应条件
Li(Et3CO)3AlH in tetrahydrofuran T=0°C;
参考文献
Tetrahedron Letters, , vol. 35, # 48 p. 9031 - 9034
反应条件
1: With methanol; 4 A molecular sieve in diethyl ether T=-40°C; 15 h; 2: With water Further stages.;
参考文献
Hang; Tian; Tang; Deng
Journal of the American Chemical Society, 2001 , vol. 123, # 50 p. 12696 - 12697
反应条件
1: 1.) LDA / 1.) THF, heptane, Et-Ph, -78 deg C, 1 h, 2.) THF, heptane, Et-Ph, 10 min, -78 deg C
2: NaBH4 / methanol / -20 °C
View Scheme
参考文献
Paris, Marielle; Fehrentz, Jean-Alain; Heitz, Annie; Loffet, Albert; Martinez, Jean
Tetrahedron Letters, 1996 , vol. 37, # 47 p. 8489 - 8492
