1-甲氧基-4-(2-苯基乙基)-苯合成路线 (共 58 条)
反应条件
sodium tetrahydroborate; nickel dichloride in methanol
T=20°C; 0.416667 h;
参考文献
Khurana, Jitender M.; Kandpal, Bhaskar M.; Kukreja, Gagan; Sharma, Purnima
Canadian Journal of Chemistry, 2006 , vol. 84, # 8 p. 1019 - 1023
反应条件
nickel in ethanol
1 h; Heating;
参考文献
Albertazzi, A.; Leardini, R.; Pedulli, G.F.; Tundo, A.; Zanardi, G.
Journal of Organic Chemistry, 1984 , vol. 49, # 23 p. 4482 - 4486
反应条件
N,N,N',N,-tetramethylethylenediamine; ((Me)N2N)Ni-Cl in tetrahydrofuran
T=20°C; Kumada-Corriu-Tamao coupling reaction; 2 h; Inert atmosphere;
参考文献
Vechorkin, Oleg; Proust, Valerie; Hu, Xile
Journal of the American Chemical Society, 2009 , vol. 131, # 28 p. 9756 - 9766
反应条件
pyridine; MeCH=CHCO2Et; nickel dichloride; zinc in acetonitrile
T=20°C; 8 h; Inert atmosphere;
参考文献
Yan, Chang-Song; Peng, Yu; Xu, Xiao-Bo; Wang, Ya-Wen
Chemistry - A European Journal, 2012 , vol. 18, # 19 p. 6039 - 6048
反应条件
potassium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in tetrahydrofuran; water
Suzuki coupling reaction; 18 h; Heating;
参考文献
Molander, Gary A.; Yun, Chang-Soo
Tetrahedron, 2002 , vol. 58, # 8 p. 1465 - 1470
反应条件
1: S2O8(2-), Fe(ClO4), HClO4 / Cu(ClO4)2 / acetonitrile; H2O / Ambient temperature
2: NaOH / tetrahydrofuran; H2O
View Scheme
参考文献
Camaioni, Donald M.; Franz, James A.
Journal of Organic Chemistry, 1984 , vol. 49, # 9 p. 1607 - 1613
反应条件
1: 1-bromo-4-methoxy-benzene; bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methane With Pd0(tris(tert-butyl)phosphine)2; potassium hydroxide in 1,4-dioxane; water
T=20°C; Suzuki-Miyaura Coupling; 3 h; Inert atmosphere;
2: benzyl bromide With potassium hydroxide in 1,4-dioxane; water
T=60°C; Suzuki-Miyaura Coupling; 24 h; Inert atmosphere;
参考文献
Endo, Kohei; Ishioka, Takafumi; Ohkubo, Takahiro; Shibata, Takanori
Journal of Organic Chemistry, 2012 , vol. 77, # 17 p. 7223 - 7231
反应条件
palladium diacetate; triphenyl silane in tetrahydrofuran
T=20°C; 7 h;
参考文献
Cacchi, Sandro; Fabrizi, Giancarlo; Goggiamani, Antonella; Persiani, Daniela
Organic Letters, 2008 , vol. 10, # 8 p. 1597 - 1600
反应条件
anhydrous iron chloride; Ipr.HCl in tetrahydrofuran
T=0 - 40°C; 1.66667 h;
参考文献
Ghorai, Sujit K.; Jin, Masayoshi; Hatakeyama, Takuji; Nakamura, Masaharu
Organic Letters, 2012 , vol. 14, # 4 p. 1066 - 1069
反应条件
nickel in ethanol
Heating;
参考文献
Clark, Peter David; Ewing, David F.; Kerrigan, Frank; Scrowston, Richard M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 615 - 622