(2R,6r)-2,6-庚二醇合成路线 （共 9 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 1 h;
参考文献
Li, Xiaoyong; Burrell, Carmin E.; Staples, Richard J.; Borhan, Babak
Journal of the American Chemical Society, 2012 , vol. 134, # 22 p. 9026 - 9029
反应条件
sodium hydroxide in methanol; water 1 h; Reflux;
参考文献
Leijondahl, Karin; Boren, Linnea; Braun, Roland; Baeckvall, Jan-E.
Organic Letters, 2008 , vol. 10, # 10 p. 2027 - 2030
反应条件
1: 70 percent / DIBAL / -78 °C 2: 1.) Im.; 2.) Raney Ni 3: 98 percent / LDA / tetrahydrofuran 4: 81 percent / DIBAL 5: 1.) TBAF; 2.) Raney Ni View Scheme
参考文献
Solladie, Guy; Huser, Nathalie; Garcia-Ruano, Jose Luis; Adrio, Javier; Carmen Carreno; Tito, Amelia
Tetrahedron Letters, 1994 , vol. 35, # 29 p. 5297 - 5300
反应条件
1: 98 percent / LDA / tetrahydrofuran 2: 81 percent / DIBAL 3: 1.) TBAF; 2.) Raney Ni View Scheme
参考文献
Solladie, Guy; Huser, Nathalie; Garcia-Ruano, Jose Luis; Adrio, Javier; Carmen Carreno; Tito, Amelia
Tetrahedron Letters, 1994 , vol. 35, # 29 p. 5297 - 5300
反应条件
1: 1.) Im.; 2.) Raney Ni 2: 98 percent / LDA / tetrahydrofuran 3: 81 percent / DIBAL 4: 1.) TBAF; 2.) Raney Ni View Scheme
参考文献
Solladie, Guy; Huser, Nathalie; Garcia-Ruano, Jose Luis; Adrio, Javier; Carmen Carreno; Tito, Amelia
Tetrahedron Letters, 1994 , vol. 35, # 29 p. 5297 - 5300
反应条件
(Ph)2SiH2; potassium carbonate; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; (S,S)-2,2''-bis[(R)-1-(diethylphosphino)ethyl]-1,1'-biferrocene 1.) THF, -30 degC, 30 h; 2.) MeOH; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kuwano, Ryoichi; Sawamura, Masaya; Shirai, Junya; Takahashi, Masatoshi; Ito, Yoshihiko
Tetrahedron Letters, 1995 , vol. 36, # 29 p. 5239 - 5242
反应条件
1: Jacobsen's (S,S)-(salen)Co(III) catalyst; water; acetic acid / tetrahydrofuran / 20 h / Cooling with ice 2: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C View Scheme
参考文献
Li, Xiaoyong; Burrell, Carmin E.; Staples, Richard J.; Borhan, Babak
Journal of the American Chemical Society, 2012 , vol. 134, # 22 p. 9026 - 9029
反应条件
tetrabutyl ammonium fluoride; nickel Yield given. Multistep reaction;
参考文献
Solladie, Guy; Huser, Nathalie; Garcia-Ruano, Jose Luis; Adrio, Javier; Carmen Carreno; Tito, Amelia
Tetrahedron Letters, 1994 , vol. 35, # 29 p. 5297 - 5300
反应条件
1: 81 percent / DIBAL 2: 1.) TBAF; 2.) Raney Ni View Scheme
参考文献
Solladie, Guy; Huser, Nathalie; Garcia-Ruano, Jose Luis; Adrio, Javier; Carmen Carreno; Tito, Amelia
Tetrahedron Letters, 1994 , vol. 35, # 29 p. 5297 - 5300
