(R)-α-氨基环己基乙酸合成路线 （共 10 条）
反应条件
hydrogenchloride; hydrogen in water; isopropyl alcohol T=50 - 60°C; 6 - 8 h;
参考文献
DEGUSSA AG
Patent: WO2005/14526 A1, 2005 ;
Location in patent: Page/Page column 12 ;
反应条件
hydrogen; platinum(IV) oxide
参考文献
Journal of the American Chemical Society, , vol. 104, # 1 p. 363 - 365
参考文献
Journal of the American Chemical Society, , vol. 104, # 1 p. 363 - 365
反应条件
2: quinine 3: aqueous HCl View Scheme
参考文献
Journal of the Chemical Society, , p. 2073,2077
反应条件
hydrogen bromide Heating;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 31, p. 4563 - 4580
参考文献
Journal of the Chemical Society, , p. 2073,2077
反应条件
(i) aq. HCl, (ii) (hydrogenation); Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 20, # 2 p. 279 - 290
反应条件
1: quinine 2: aqueous HCl View Scheme
参考文献
Journal of the Chemical Society, , p. 2073,2077
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Devant, Ralf; Braun, Manfred
Chemische Berichte, 1986 , vol. 119, # 7 p. 2191 - 2207
反应条件
1: With sodium carbonate in water; acetone T=20°C; 16 h; 2: With potassium hydrogensulfate in water pH=1;
参考文献
King, Amber M.; Salome, Christophe; Dinsmore, Jason; Salome-Grosjean, Elise; De Ryck, Marc; Kaminski, Rafal; Valade, Anne; Kohn, Harold
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4815 - 4830
