1: 4-bromothiophene-3-carboxylic acid With lithium diisopropyl amide in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexane T=-78°C; 1 h; 2: N-methoxy-N-methyl-4-pyridinecarboxamide in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexane T=-78 - 20°C; 1 h;