1: With lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 2 h; 2: With hydrogenchloride in tetrahydrofuran; water; ethyl acetate T=0°C;

sodium carbonate; bis(dibenzylideneacetone)-palladium(0); dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine in 1,4-dioxane; water Suzuki-Miyaura cross-coupling; 48 h; Inert atmosphereReflux;

pyridinium chlorochromate in dichloromethane 1.5 h; Ambient temperature;