N-(5-乙酰基-2-(苄氧基)苯基)甲磺酰胺合成路线 （共 7 条）
参考文献
Washburn; Sher; Poss; Girotra; McCann; Gavai; Mikkilineni; Mathur; Cheng; Dejneka; Sun; Wang; Harper; Russell; Slusarchyk; Skwish; Allen; Hillyer; Frohlich; Abboa-Offei; Cap; Waldron; George; Tesfamariam; Ciosek Jr.; Ryono; Young; Dickinson; Seymour; Arbeeny; Gregg
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 23 p. 3035 - 3039
反应条件
pyridine in n-heptane; chloroform
参考文献
Bristol-Myers Squibb Company
Patent: US5776983 A1, 1998 ;
反应条件
1.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C 1.2: 3 h / 20 °C / Reflux 2.1: platinum(IV) oxide; hydrogen / tetrahydrofuran; toluene / 24 h / 25 °C / 772.58 Torr 3.1: pyridine / acetonitrile / 1 h / 25 °C View Scheme
参考文献
De Koning, Pieter D.; Gladwell, Iain R.; Moses, Ian B.; Panesar, Maninder S.; Pettman, Alan J.; Thomson, Nicholas M.
Organic Process Research and Development, 2011 , vol. 15, # 6 p. 1247 - 1255
反应条件
1: platinum(IV) oxide; hydrogen / tetrahydrofuran; toluene / 24 h / 25 °C / 772.58 Torr 2: pyridine / acetonitrile / 1 h / 25 °C View Scheme
参考文献
De Koning, Pieter D.; Gladwell, Iain R.; Moses, Ian B.; Panesar, Maninder S.; Pettman, Alan J.; Thomson, Nicholas M.
Organic Process Research and Development, 2011 , vol. 15, # 6 p. 1247 - 1255
反应条件
1.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C 1.2: 3 h / 20 °C / Reflux 2.1: platinum(IV) oxide; hydrogen / tetrahydrofuran; toluene / 24 h / 25 °C / 772.58 Torr 3.1: pyridine / acetonitrile / 1 h / 25 °C View Scheme
参考文献
De Koning, Pieter D.; Gladwell, Iain R.; Moses, Ian B.; Panesar, Maninder S.; Pettman, Alan J.; Thomson, Nicholas M.
Organic Process Research and Development, 2011 , vol. 15, # 6 p. 1247 - 1255
反应条件
ammonium formate; palladium 10 on activated carbon in methanol 3 h; Heating / reflux;
参考文献
Piramal Life Sciences Limited
Patent: US7759387 B2, 2010 ;
Location in patent: Page/Page column 78 ;
反应条件
tetra-n-butylammonium tribromide in tetrahydrofuran; methanol
T=25°C; 1.75 h;
参考文献
De Koning, Pieter D.; Gladwell, Iain R.; Moses, Ian B.; Panesar, Maninder S.; Pettman, Alan J.; Thomson, Nicholas M.
Organic Process Research and Development, 2011 , vol. 15, # 6 p. 1247 - 1255
