(1R,2r)-2-氨基-环己烷羧酸乙酯合成路线 （共 9 条）
反应条件
1: 91 percent / H2 / 10percent Pt/C / ethanol / 760 Torr / Ambient temperature 2: 1.) bromine, NaOH; 2.) HCl / 1.) water, 75 deg C, 2 min; 2.) reflux, 3 h View Scheme
参考文献
Booth, Harold; Khedhair, Khedhair A.; Al-Shirayda, Hatif A. R. Y.
Tetrahedron, 1988 , vol. 44, # 5 p. 1465 - 1476
反应条件
sodium cyanoborohydride; acetic acid in ethyl acetate T=0°C; 6 h;
参考文献
He, Tian; Gao, Wen-Chao; Wang, Wei-Kun; Zhang, Chi
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 5 p. 1113 - 1118
反应条件
1: ammonium acetate / methanol / 48 h / 20 °C 2: sodium cyanoborohydride; acetic acid / ethyl acetate / 6 h / 0 °C View Scheme
参考文献
He, Tian; Gao, Wen-Chao; Wang, Wei-Kun; Zhang, Chi
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 5 p. 1113 - 1118
反应条件
hydrogenchloride; sodium hydroxide; bromine 1.) water, 75 deg C, 2 min; 2.) reflux, 3 h; Yield given. Multistep reaction;
参考文献
Booth, Harold; Khedhair, Khedhair A.; Al-Shirayda, Hatif A. R. Y.
Tetrahedron, 1988 , vol. 44, # 5 p. 1465 - 1476
反应条件
acetic acid; platinum Hydrogenation;
参考文献
Clemo et al.
Journal of the Chemical Society, 1938 , p. 1183,1186
Full Text Show Details
Huenig; Kahanek
Chemische Berichte, 1953 , vol. 86, p. 518,521, 522
反应条件
1: 66 percent 2: 38 percent / lithium aluminium hydride / diethyl ether View Scheme
参考文献
Booth, Harold; Khedhair, Khedhair A.; Al-Shirayda, Hatif A. R. Y.
Tetrahedron, 1988 , vol. 44, # 5 p. 1465 - 1476
反应条件
1: aqueous hydrochloric acid View Scheme
参考文献
Huenig; Kahanek
Chemische Berichte, 1953 , vol. 86, p. 518,521, 522
反应条件
1: aqueous hydrochloric acid View Scheme
参考文献
Huenig; Kahanek
Chemische Berichte, 1953 , vol. 86, p. 518,521, 522
参考文献
Huenig; Kahanek
Chemische Berichte, 1953 , vol. 86, p. 518,521, 522
