5-(4-氯苯基)恶唑-4-甲酸合成路线 (共 4 条)
反应条件
sodium hydroxide in tetrahydrofuran; water
参考文献
Davies, James R.; Kane, Peter D.; Moody, Christopher J.
Tetrahedron, 2004 , vol. 60, # 18 p. 3967 - 3977
反应条件
1: 89 percent / 4-acetamidobenzenesulfonyl azide; triethylamine / acetonitrile / 16 h / 20 °C 2: 55 percent / dirhodium tetraoctanoate / CH2Cl2 / Heating 3: 65 percent / triphenylphosphine; iodine; triethylamine / CH2Cl2 / 16 h 4: 87 percent / NaOH / tetrahydrofuran; H2O View Scheme
参考文献
Tetrahedron, , vol. 60, # 18 p. 3967 - 3977
反应条件
1: 55 percent / dirhodium tetraoctanoate / CH2Cl2 / Heating 2: 65 percent / triphenylphosphine; iodine; triethylamine / CH2Cl2 / 16 h 3: 87 percent / NaOH / tetrahydrofuran; H2O View Scheme
参考文献
Tetrahedron, , vol. 60, # 18 p. 3967 - 3977
反应条件
1: 65 percent / triphenylphosphine; iodine; triethylamine / CH2Cl2 / 16 h 2: 87 percent / NaOH / tetrahydrofuran; H2O View Scheme
参考文献
Tetrahedron, , vol. 60, # 18 p. 3967 - 3977