(1S,2s)-boc-2-氨基环戊烷羧酸合成路线 （共 14 条）
反应条件
lithium hydroxide in methanol; water T=0°C; 17 h;
参考文献
Tilley, Jefferson W.; Danho, Waleed; Shiuey, Shian-Jun; Kulesha, Irina; Swistok, Joseph; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3774 - 3783
反应条件
1: AcOH / ethanol 2: NaCNBH3 3: LiOH 4: H2 / Pd/C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 46 p. 15067 - 15073
反应条件
1: H2 / Pd/C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 46 p. 15067 - 15073
反应条件
1: LiOH 2: H2 / Pd/C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 46 p. 15067 - 15073
反应条件
1: 93 percent / H2 / 10 percent Pd/C / dimethylformamide / 3 h / 2585.7 Torr 2: 85 percent / LiOH / H2O; methanol / 17 h / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 21 p. 3774 - 3783
反应条件
1: 63 percent / triphenylphosphine, hydrazoic acid, diethyl azodicarboxylate / benzene / 3 h / Ambient temperature 2: 93 percent / H2 / 10 percent Pd/C / dimethylformamide / 3 h / 2585.7 Torr 3: 85 percent / LiOH / H2O; methanol / 17 h / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 21 p. 3774 - 3783
反应条件
1: 93 percent / H2 / 10 percent Pd/C / dimethylformamide / 3 h / 2585.7 Torr 2: 85 percent / LiOH / H2O; methanol / 17 h / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 21 p. 3774 - 3783
反应条件
sodium hydroxide in 1,4-dioxane; water 1 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 53, # 23 p. 7975 - 7984
反应条件
1: 99 percent / SnCl4 / CH2Cl2 / 24 h / Ambient temperature 2: 85 percent / NaOH / dioxane; H2O / 2 h / Ambient temperature 3: 73 percent / diphenylphosphorylazide, Et3N / 18 h / 80 °C 4: 81 percent / Raney-Nickel / methanol / 4 h / Heating 5: NaOH / dioxane; H2O / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 53, # 23 p. 7975 - 7984
反应条件
1: 73 percent / diphenylphosphorylazide, Et3N / 18 h / 80 °C 2: 81 percent / Raney-Nickel / methanol / 4 h / Heating 3: NaOH / dioxane; H2O / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 53, # 23 p. 7975 - 7984
