(1S,2s)-boc-2-氨基环戊烷羧酸合成路线 （共 14 条）
反应条件
1: 85 percent / NaOH / dioxane; H2O / 2 h / Ambient temperature 2: 73 percent / diphenylphosphorylazide, Et3N / 18 h / 80 °C 3: 81 percent / Raney-Nickel / methanol / 4 h / Heating 4: NaOH / dioxane; H2O / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 53, # 23 p. 7975 - 7984
反应条件
1: 81 percent / Raney-Nickel / methanol / 4 h / Heating 2: NaOH / dioxane; H2O / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 53, # 23 p. 7975 - 7984
参考文献
Journal of the American Chemical Society, , vol. 126, # 46 p. 15067 - 15073
反应条件
1.1: Et3N; ethyl chloroformate / tetrahydrofuran / 0.33 h / 0 °C 1.2: aq. NaN3 / tetrahydrofuran / 0.33 h / 0 °C 2.1: 2.15 g / benzene / 0.5 h / Heating 3.1: 89 percent / CuCl / dimethylformamide / 0.75 h / 20 °C 4.1: H2 / Pd/C / methanol / 12 h / 2844.31 Torr View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 46 p. 15067 - 15073
