1: 85 percent / ZnI2 / 3 h / 25 °C
2: LiN(iPr)2 / tetrahydrofuran; hexane / 2 h / -78 °C
3: tetrahydrofuran / -78 °C / var. solvents; var. bases; var. complex reagents; var. temp.; var. subst. 1-cyano-1-O-substituted allyl lithium compounds
View Scheme
1: (E)-cinnamaldehyde With 1H-imidazole; N-ethyl-N,N-diisopropylamine; triazolium salt in tetrahydrofuran
T=40°C; 15 h;
2: benzylamine in tetrahydrofuran
T=20 - 25°C; 1 h; Further stages.;
参考文献
Bode, Jeffrey W.; Sohn, Stephanie S.
Journal of the American Chemical Society, 2007 , vol. 129, # 45 p. 13798 - 13799
