2-硝基-4-三氟甲基苯硫酚合成路线 （共 7 条）
反应条件
1: With alpha-D-glucopyranose in ethanol T=55°C; 0.166667 h; 2: With potassium hydroxide in ethanol T=20°C; 0.166667 h;
参考文献
Rodygin, Konstantin S.; Rubtsova, Svetlana A.; Kutchin, Alexander V.; Slepukhin, Pavel A.
Phosphorus, Sulfur and Silicon and the Related Elements, 2011 , vol. 186, # 9 p. 1885 - 1894
反应条件
sodium sulfide in carbon disulfide; butanone 12 h; Ambient temperature;
参考文献
Gazzetta Chimica Italiana, , vol. 110, # 5/6 p. 301 - 304
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1125 - 1128
反应条件
1: 2-nitro-4-(trifluoromethyl)benzenethiol With potassium hydroxide in ethanol T=20°C; 0.166667 h; 2: ethyl iodide in ethanol T=40 - 45°C; 0.333333 h;
参考文献
Rodygin, Konstantin S.; Rubtsova, Svetlana A.; Kutchin, Alexander V.; Slepukhin, Pavel A.
Phosphorus, Sulfur and Silicon and the Related Elements, 2011 , vol. 186, # 9 p. 1885 - 1894
反应条件
potassium hydroxide in methanol; water
参考文献
Zeneca Limited
Patent: US5451681 A1, 1995 ;
反应条件
1: 2-nitro-4-(trifluoromethyl)benzenethiol With potassium hydroxide in ethanol T=20°C; 0.166667 h; 2: methyl iodide in ethanol T=40 - 45°C; 0.333333 h;
参考文献
Rodygin, Konstantin S.; Rubtsova, Svetlana A.; Kutchin, Alexander V.; Slepukhin, Pavel A.
Phosphorus, Sulfur and Silicon and the Related Elements, 2011 , vol. 186, # 9 p. 1885 - 1894
反应条件
hydrogen; palladium on activated charcoal in tetrahydrofuran
参考文献
Medicinal Chemistry Research, , vol. 10, # 1 p. 19 - 29
