1: 94 percent / SOCl2 / 2 h / Heating 2: 98 percent / NaN3 / acetonitrile / 4 h / Ambient temperature 3: NaBH4 / acetonitrile / 0.08 h / -20 °C 4: toluene / 0.5 h / Heating 5: toluene / 0.5 h / Heating 6: 70 percent / concd. HCl / methanol / 6 h / Heating View Scheme

sodium borohydride in sodium hydrogencarbonate

1: 94 percent / SOCl2 / 2 h / Heating 2: 98 percent / NaN3 / acetonitrile / 4 h / Ambient temperature 3: toluene / 1.5 h / Heating 4: KOH / toluene; H2O / 0.25 h / 0 °C 5: 1 N HCl / H2O 6: 90 percent / 1 N NaOH / methanol / 1.5 h / Ambient temperature View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: benzene / 30 h / Heating<br />2: phosphoryl chloride / 10 h / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: benzene / 30 h / Heating<br />2: phosphoryl chloride / 10 h / Heating<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11131068', constants.ctx, '0')">tris(2-hydroxyethyl)ammonium acetate</a> <br />T=85&deg;C;&nbsp;Knoevenagel condensation;&nbsp;3&nbsp;h;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '10774525', constants.ctx, '0')">ammonium acetate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '635760', constants.ctx, '0')">toluene</a> <br /> <br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: piperidine / ethanol / Heating<br />2: CF₃COOH / Ambient temperature<br /> <br /> &nbsp;

Stage #1: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342940', constants.ctx, '0')">sodium hydroxide</a> <br /> <br />Stage #2: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098214', constants.ctx, '0')">hydrogenchloride</a> <br /> <br /> &nbsp;