2-羟基-4,5-二甲氧基苯甲醛合成路线 （共 33 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=130°C; 8 h;
参考文献
Kawase, Yoshiyuki; Yamaguchi, Seiji; Horita, Hisanori; Takeno, Junko; Kameyama, Hideaki
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 4 p. 1153 - 1155
反应条件
1: 1.) Zn / 1.) THF, 30 min, 2.) THF, RT, 20 min 2: p-TSA / toluene / Heating View Scheme
参考文献
Aukrust, I.R.; Noushabadi, M.; Skatteboel, L.
Polish Journal of Chemistry, 1994 , vol. 68, # 11 p. 2167 - 2174
参考文献
Jackson,A.H.; Martin,J.A.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 2222 - 2229
反应条件
in xylene 4 h; Heating;
参考文献
Harayama, Takashi; Katsuno, Keiko; Nishioka, Hiromi; Fujii, Masako; Nishita, Yoshitaka; et al.
Heterocycles, 1994 , vol. 39, # 2 p. 613 - 622
参考文献
Mali, R. S.; Yadav, V. J.; Zaware, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, p. 759 - 760
反应条件
sodium acetate T=180°C;
参考文献
Singh et al.
Journal of Scientific and Industrial Research, 1956 , vol. 15 B, p. 190,192
反应条件
1: 4,5-dimethoxy-2-hydroxy-benzaldehyde With potassium carbonate in butanone T=0°C; 0.166667 h; Inert atmosphere; 2: 1-bromo-2-propanone in butanone T=90°C; 4 h; Inert atmosphere;
参考文献
COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH; VISHWAKARMA, Ram Asrey; SAWANT, Sanghapal Damodhar; SINGH, Parvinder Pal; DAR, Abid Hamid; SHARMA, Parduman Raj; SAXENA, Ajit Kumar; NARGOTRA, Amit; KOLLURU, Anjaneya Aravind Kumar; MUDUDUDDLA, Ramesh; QAZI, Asif Khurshid; HUSSAIN, Aashiq; CHANAURIA, Nayan
Patent: WO2013/140417 A1, 2013 ;
Location in patent: Page/Page column 17 ;
反应条件
potassium carbonate in acetone 6 h; Reflux;
参考文献
Zhang, Jie; Li, Liqi; Wang, Yongxiang; Wang, Wenjing; Xue, Jijun; Li, Ying
Organic Letters, 2012 , vol. 14, # 17 p. 4528 - 4530
反应条件
1: in acetonitrile
T=80°C; 0.166667 h;
2: With N-bromosuccinmide in acetonitrile
T=80°C; 8 h; regioselective reaction;
参考文献
Singh, Parvinder Pal; Thatikonda, Thanusha; Kumar, K. A. Aravinda; Sawant, Sanghapal D.; Singh, Baldev; Sharma, Amit Kumar; Sharma; Singh, Deepika; Vishwakarma, Ram A.
Journal of Organic Chemistry, 2012 , vol. 77, # 13 p. 5823 - 5828
反应条件
1: sodium borohydride / tetrahydrofuran
2: 85 percent / (KSO3)2NO / H2O / Na2HPO4-NaH2PO4 buffer pH=5.8
View Scheme
参考文献
Deya, Pedro M.; Dopico, Mercedes; Raso, Angel Garcia; Morey, Jeronimo; Saa, Jose M.
Tetrahedron, 1987 , vol. 43, # 15 p. 3523 - 3532
