2-羟基-4,5-二甲氧基苯甲醛合成路线 （共 33 条）
反应条件
1: pyridine
2: acetone; aqueous potassium permanganate solution
3: aqueous KOH-solution
View Scheme
参考文献
Head; Robertson
Journal of the Chemical Society, 1931 , p. 2432
反应条件
piperidine; ethanol; acetic acid
参考文献
Baltzly
Journal of the American Chemical Society, 1952 , vol. 74, p. 2692
反应条件
1: 75 percent / Et3N / CH2Cl2 / 1 h / 0 °C
2: 97 percent / NaClO2; aq. H2O2; sodium phosphate dihydrate / acetonitrile / 3 h / 10 °C
3: SOCl2; pyridine / CH2Cl2 / 1.5 h / Heating
4: 578 mg / Et3N / CHCl3 / 12 h / 20 °C
5: 93 percent / Bu3P; 1,3-bis-(diphenylphosphino)propane; iPr2Net / Pd(OAc)2 / dimethylformamide / 0.5 h / Heating
View Scheme
参考文献
Harayama, Takashi; Akiyama, Toshihiko; Nakano, Yuichiro; Shibaike, Kentaro
Heterocycles, 1998 , vol. 48, # 10 p. 1989 - 1992
